Note: The job is a remote job and is open to candidates in USA. Helix is dedicated to transforming healthcare through genomics, aiming to integrate genomic data into clinical practice. The Senior Cloud Infrastructure Engineer will be responsible for architecting and securing the cloud infrastructure, collaborating with various teams to enhance support for product development while ensuring reliability and scalability.
Responsibilities
- Lead the strategic evolution of our cloud infrastructure, proactively identifying opportunities to enhance support for product teams. Drive innovation in cloud infrastructure strategy
- Collaborate with product management, scientists, and engineering teams to understand intricate requirements and develop comprehensive, forward-thinking engineering designs
- Architect and implement highly reliable and massively scalable cloud infrastructure solutions on AWS and potentially other platforms, anticipating future growth and evolving user and health system needs. Ensure alignment with the long-term architectural vision
- Champion and promote Cloud Engineering best practices across teams, influencing technical direction and standards
- Strategically lead initiatives to optimize cloud spending, demonstrating a strong understanding of budget ROI and resource utilization
- Spearhead the development and advancement of sophisticated CI/CD pipelines for highly automated, efficient, and resilient build, test, and deployment processes
- Define and implement comprehensive observability strategies, selecting and managing advanced tools to provide deep insights into system health and performance, and proactively predict and mitigate potential issues
- Mentor and guide Infrastructure Engineers by providing technical expertise, constructive feedback, coaching, and support to foster their professional development and drive excellence in cloud operations
Skills
- Experience integrating and utilizing AI-powered tools for proactive observability, cost optimization, and code analysis to improve cloud operations and development
- Ability to evaluate and recommend new AI tools to enhance cloud operations and development workflows
- A strong passion for improving people's lives through access to better information about their DNA
- Minimum of 5+ years of progressive hands-on experience in cloud architecture, deployment, and operations, demonstrating increasing technical leadership and strategic impact
- 5+ years of significant software development experience in one of the following: Go, Python, or a similar language, with a proven track record of designing and implementing complex cloud-native applications and infrastructure
- 5+ years of in-depth experience in cloud computing, with at least 5 years of demonstrable expert-level experience with a broad range of AWS services and a deep understanding of cloud architectural patterns
- Participate in a rotating on-call schedule, demonstrating ownership, providing leadership during incidents, and driving root cause analysis and preventative measures
- Expert-level sysadmin skills in a Linux environment, including mastery of Bash and other scripting languages for advanced automation, diagnostics, and performance tuning
- Extensive experience in designing and implementing infrastructure-as-code tooling/frameworks — e.g., Terraform and CDK — at scale, including defining best practices and standards
- A strong affinity for and proven ability to champion an engineering culture that emphasizes Agile methodologies, DevOps principles, and continuous delivery practices across teams
- Exceptional communication and interpersonal skills, with the proven ability to articulate complex technical concepts clearly and persuasively to diverse audiences, including executive stakeholders
- Direct experience with CircleCi, Rollbar and Pagerduty
- Familiarity with full-stack development
- Familiarity with regulated software systems and entities
- AWS or other cloud certifications
- Multi Cloud experience (AWS, GCP, Azure)
- BS+ in Computer Science; coursework in genetics or bioinformatics
Benefits
- Expected Helix Discretionary Annual Bonus: 10% of your annual salary
- Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.
- Comprehensive Health Insurance with Date of Hire eligibility
- Above average employer paid premium coverage
- 12 weeks Helix Paid Parental Leave option
- 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
- Comprehensive Well-Being Benefits
- Flexible PTO
- Remote options for many roles and a home office stipend
Company Overview
Helix is a population genomics company that is working to advance genomics research and integrate genomic data into clinical care. It was founded in 2015, and is headquartered in San Mateo, California, USA, with a workforce of 51-200 employees. Its website is http://www.helix.com.Company H1B Sponsorship
Helix has a track record of offering H1B sponsorships, with 3 in 2026, 4 in 2025, 3 in 2024, 3 in 2023, 1 in 2022. Please note that this does not guarantee sponsorship for this specific role.